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  <xs:element id="imrx_LeaseTerminationOnDecember312022Member" abstract="true" name="LeaseTerminationOnDecember312022Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_TwoThousandTwentyOneEmployeeStockPurchasePlanMember" abstract="true" name="TwoThousandTwentyOneEmployeeStockPurchasePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_BioArkiveIncMember" abstract="true" name="BioArkiveIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_GovernmentSecuritiesMember" abstract="true" name="GovernmentSecuritiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_NoticePeriodForContractTermination" abstract="false" name="NoticePeriodForContractTermination" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="imrx_NumberOfLeasesObligationsAssumed" abstract="false" name="NumberOfLeasesObligationsAssumed" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="imrx_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" abstract="false" name="LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_EquityDistributionAgreementMember" abstract="true" name="EquityDistributionAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_AreaOfPropertyUnderLease" abstract="false" name="AreaOfPropertyUnderLease" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:areaItemType"/>
  <xs:element id="imrx_EarningsPerShareBasicAndDilutedEPSAbstract" abstract="true" name="EarningsPerShareBasicAndDilutedEPSAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="imrx_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsIntrinsicValueAbstract" abstract="true" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsIntrinsicValueAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="imrx_AtMarketOfferingMember" abstract="true" name="AtMarketOfferingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_LeasePayments" abstract="false" name="LeasePayments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_LeaseTerminationOnApril302032Member" abstract="true" name="LeaseTerminationOnApril302032Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_UnauditedInterimFinancialInformationPolicyPolicyTextBlock" abstract="false" name="UnauditedInterimFinancialInformationPolicyPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="imrx_SaleOfStockProceedsBeforeDeductingOfferingCostsPayable" abstract="false" name="SaleOfStockProceedsBeforeDeductingOfferingCostsPayable" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_OperatingLeaseAdditionalInformationAbstract" abstract="true" name="OperatingLeaseAdditionalInformationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="imrx_OfficeSpaceInCambridgeMassachusettsNewYorkSanFranciscoCaliforniaMember" abstract="true" name="OfficeSpaceInCambridgeMassachusettsNewYorkSanFranciscoCaliforniaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_EquityOfferingCombinedAggregateDateOfEffectivePeriod" abstract="false" name="EquityOfferingCombinedAggregateDateOfEffectivePeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="imrx_AccruedLiabilitiesDisclosureTextBlock" abstract="false" name="AccruedLiabilitiesDisclosureTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="imrx_MarketableSecuritiesCurrentAbstract" abstract="true" name="MarketableSecuritiesCurrentAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="imrx_CreditLossRelatedToShortTermInvestments" abstract="false" name="CreditLossRelatedToShortTermInvestments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_OfficeLeaseInSanDiegoCalifornia2020Member" abstract="true" name="OfficeLeaseInSanDiegoCalifornia2020Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_LabEquipmentMember" abstract="true" name="LabEquipmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_AccruedContractResearchExpensesCurrent" abstract="false" name="AccruedContractResearchExpensesCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_MarketableSecuritiesFairValueDisclosure" abstract="false" name="MarketableSecuritiesFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_EquityOfferingCombinedAggregateAmount" abstract="false" name="EquityOfferingCombinedAggregateAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_TwoThousandTwentyOneIncentiveAwardPlanMember" abstract="true" name="TwoThousandTwentyOneIncentiveAwardPlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_SaleOfStockNetProceedsAfterDeductingUnderwritingDiscountAndCommission" abstract="false" name="SaleOfStockNetProceedsAfterDeductingUnderwritingDiscountAndCommission" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_PercentageOnGrossProceedsFromCommonStockSoldForSalesAgentCommission" abstract="false" name="PercentageOnGrossProceedsFromCommonStockSoldForSalesAgentCommission" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="imrx_UnderwritingOfferingMember" abstract="true" name="UnderwritingOfferingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_PropertyAndEquipmentInAccountsPayableOrAccruedExpenses" abstract="false" name="PropertyAndEquipmentInAccountsPayableOrAccruedExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_MaximumAggregateGrossProceedsFromEquityOffering" abstract="false" name="MaximumAggregateGrossProceedsFromEquityOffering" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_PercentageOfAggregateNumberOfSharesOutstanding" abstract="false" name="PercentageOfAggregateNumberOfSharesOutstanding" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="imrx_SandlerAndCoMember" abstract="true" name="SandlerAndCoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_OfficeAndLaboratorySpaceInSanDiegoCaliforniaMember" abstract="true" name="OfficeAndLaboratorySpaceInSanDiegoCaliforniaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_LeaseTerminationOnMarch312024Member" abstract="true" name="LeaseTerminationOnMarch312024Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_OfferingCostPayable" abstract="false" name="OfferingCostPayable" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_LeaseModificationNoncash" abstract="false" name="LeaseModificationNoncash" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_IncreaseDecreaseInRightOfUseAsset" abstract="false" name="IncreaseDecreaseInRightOfUseAsset" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="imrx_NumberOfVotesEachShare" abstract="false" name="NumberOfVotesEachShare" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="imrx_StockIncentivePlan2015Member" abstract="true" name="StockIncentivePlan2015Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="imrx_PeriodOfLeaseModification" abstract="false" name="PeriodOfLeaseModification" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
</xs:schema>
